Tottenham Hotspur: Vorm, Walker, Dier, Vertonghen (c), Davies; Mason, Stambouli; Lamela, Dembele, Eriksen; Kane
Subs: Friedel, Fazio, Rose, Paulinho, Townsend, Adebayor, Soldado
Tottenham have won all three previous League Cup encounters with Sheffield United.
The Blades have won five of their last six League Cup home games against higher division opposition.
Spurs have not kept a clean sheet in their last 11 away games in all competitions.